RESUMEN
COVID-19 is driving profound changes in global governance of human health. At the historical intersection of healthy China and the calls on building China into education powerhouse, adolescent health has become the core concern of China. Based on the practical work in school health in China, this paper makes adolescent health a priority and adolescent health promotion as a policy rationale, reviews the background of the current adolescent health promotion policy and interprets the overall thinking in the process of policy design, unconventional strategies, breakthrough policies, pilot projects and cutting-edge technologies. Beyond that, this editorial also analyzes the policy focus comprehensively, and describes the current and future national implementation of the strategy and plan of action, from a broader scope of education, health and public health under the national blueprint on Healthy China 2030 and China's Education Modernisation Plan towards 2035.
RESUMEN
The long-term immunity and functional recovery after SARS-CoV-2 infection have implications in preventive measures and patient quality of life. Here we analyzed a prospective cohort of 121 recovered COVID-19 patients from Xiangyang, China at 1-year after diagnosis. Among them, chemiluminescence immunoassay-based screening showed 99% (95% CI, 98-100%) seroprevalence 10-12 months after infection, comparing to 0.8% (95% CI, 0.7-0.9%) in the general population. Total anti-receptor-binding domain (RBD) antibodies remained stable since discharge, while anti-RBD IgG and neutralization levels decreased over time. A predictive model estimates 17% (95% CI, 11-24%) and 87% (95% CI, 80-92%) participants were still 50% protected against detectable and severe re-infection of WT SARS-CoV-2, respectively, while neutralization levels against B.1.1.7 and B.1.351 variants were significantly reduced. All non-severe patients showed normal chest CT and 21% reported COVID-19-related symptoms. In contrast, 53% severe patients had abnormal chest CT, decreased pulmonary function or cardiac involvement and 79% were still symptomatic. Our findings suggest long-lasting immune protection after SARS-CoV-2 infection, while also highlight the risk of immune evasive variants and long-term consequences for COVID-19 survivors.